相关实验视频
Updated: May 12, 2026

09:01
Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
8.4K
慢性下皮质血瘤复发的危险因素:系统性审查
SeyedAhmad SeyedAlinaghi1,2, Esmaeil Mehraeen3, Farid Farahani Rad4
1Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.
Medical journal of the Islamic Republic of Iran
|November 6, 2025
概括
慢性腹膜下血瘤 (cSDH) 的复发与炎症,凝血问题和大脑变化有关. 识别这些风险因素是更好的预防和治疗策略的关键.
科学领域:
- 神经外科 神经外科
- 神经学 神经学
- 系统审查是系统的审查.
背景情况:
- 慢性亚皮血瘤 (cSDH) 复发因子缺乏一致的发现.
- 本研究旨在确定cSDH复发风险因素及其生物机制.
研究的目的:
- 系统地审查和综合当前关于慢性腹腔内血瘤复发的文献.
- 开发一个整合性框架,将临床风险因素与潜在的生物机制联系起来.
主要方法:
- 系统的文献搜索于2024年12月在Scopus,科学网,PubMed和Embase进行.
- 根据资格标准选择了61项研究,使用NOS和PRISMA检查清单评估了偏见和方法严格性.
主要成果:
- 导致cSDH复发的关键风险因素包括格拉斯哥昏迷量表 (GCS) 的低得分,中性粒细胞的升高,抗血小板/抗凝剂的使用,男性性别,年龄较大,血液瘤大小较大,排水时间较短.
- 放射性迹象 (高密度,中线转移),并发症 (糖尿病,高血压) 和炎症/凝血功能障碍有助于复发.
- 减少复发风险与早期检测,有效的排水和较高的血清HDL水平有关.
结论:
- cSDH复发源于炎症,凝血功能障碍和大脑结构变化的复杂相互作用.
- 针对这些综合途径对于改善cSDH预防和管理至关重要.
相关概念视频
Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Increased Intracranial Pressure l: Introduction
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Cerebral Edema ll: Pathophysiology
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...

