瘤病人的加密球菌脑膜炎的非典型表现:病例报告
Jing Wei1, Haiyan Huang2, Yingyu Zhang3
1Department of Neuro and Cardiovascular Medicine, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China.
Frontiers in medicine
|November 6, 2025
概括
癌症患者的密码球菌脑膜炎 (CM) 可以呈现异常. 早期识别这种严重的中枢神经系统 (CNS) 感染对于及时诊断和治疗至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
- 神经学 神经学
背景情况:
- 加密球菌脑膜炎 (CM) 是一种严重的中枢神经系统 (CNS) 感染.
- 它主要影响免疫受损的个体,包括癌症患者.
- 在瘤学人群中,CM可以异常呈现,这给诊断带来了挑战.
研究的目的:
- 在癌症患者中报告两例具有非经典特征的恶性瘤相关CM病例.
- 突出这一群体中CM的诊断挑战和可变的临床过程.
主要方法:
- 两名患有中枢神经系统 (CNS) 感染的癌症患者的病例报告.
- 对临床表现,脑脊液 (CSF) 发现和治疗结果的分析.
- 对瘤患者真菌感染的诊断考虑的审查.
主要成果:
- 描述了两例不典型表现的恶性瘤相关的CM病例.
- 病例1:肺状细胞癌患者轻微的脑液多细胞化和正常的开口压力,他恢复了.
- 病例2:患有慢性淋巴细胞白血病的患者同时患有密码球菌和性脑膜炎,明显的白血球症,脑液压升高,治疗反应不佳.
结论:
- 癌症患者的密码球菌脑膜炎可以表现出可变和非经典的特征.
- 早期识别和考虑真菌中枢神经系统感染至关重要,即使没有典型症状.
- 及时诊断和适当的抗真菌治疗对于在免疫受损的个体中管理CM至关重要.
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