使用三环抗抑郁药或色胺-北上腺素再吸收抑制剂与选择性色胺再吸收抑制剂对患有多发性硬化症的人尿路感染风险的影响:一项嵌套病例对照研究

Melissa W Y Leung1, Ewoudt M W van de Garde1,2, Bernard M J Uitdehaag3

  • 1Division Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands.

概括

在多发性硬化症 (MS) 患者中,使用三环抗抑郁药 (TCA) /氨酸 - 上腺素再吸收抑制剂 (SNRI) 与选择性氨酸再吸收抑制剂 (SSRI) 相比,不增加尿路感染 (UTI) 风险. 使用TCA/SNRI与较高的尿路感染风险有关,而非抗抑郁药的使用.

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