在治疗维生素D治疗的儿科患者中,治疗前后评估眼睛表面参数
Abdulvahit Asik1, Gözde Aksoy Aydemir2, Emre Aydemir2
1Department of Pediatrics, Adıyaman University Education and Research Hospital, Adıyaman, Turkey.
概括
儿科维生素D缺乏症 (VDD) 与干眼疾病 (DED) 症状有关. 在严重的VDD病例中,治疗改善了DED,这表明在这些症状的儿童中应考虑VDD.
科学领域:
- 眼科医生 眼科 眼科
- 儿科 儿科 儿科
- 内分泌学 在内分泌学.
背景情况:
- 维生素D缺乏症 (VDD) 在儿童群体中很普遍.
- 患有VDD的儿童的眼表面健康需要进一步调查.
- 干眼疾病 (DED) 症状可能会影响儿童的生活质量.
研究的目的:
- 评估VDD的儿科患者治疗后的眼睛表面参数.
- 评估VDD严重程度和DED之间的相关性.
- 为了确定VDD处理对眼睛表面参数的有效性.
主要方法:
- 一项前性病例控制研究,涉及83名患有VDD的儿科患者和86名健康对照.
- 评估眼睛表面疾病指数 (OSDI),眼膜破裂时间 (Tf-BUT),Schirmer 1测试和结膜印象细胞学 (CIC).
- 根据缺陷严重程度,VDD组分为三个子组;治疗后的值进行了比较.
主要成果:
- 与对照组相比,患有VDD的儿童表现出明显较差的眼表面参数,这表明DED的患病率更高.
- 治疗后最明显的DED症状和显著的改善在最严重的VDD (VDD亚组1) 的亚组中观察到.
- 在治疗VDD最不严重的子组 (VDD子组3) 后,没有注意到眼睛表面参数的显著改善.
结论:
- 维生素D缺乏 (VDD) 应在儿童干眼病 (DED) 的差异诊断中考虑.
- 严重的VDD可以加剧儿童的DED症状.
- 治疗VDD可能会导致眼睛表面参数和DED症状的改善,特别是在严重的情况下.
相关概念视频
01:23Role of Skin in Vitamin D Synthesis
7.5K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
7.5K
01:27Open Angle Glaucoma: Treatment
940
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
940
01:28Angle Closure Glaucoma: Treatment
1.1K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.1K