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Updated: Jan 12, 2026

Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling
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临床抗体光链的自上而下质谱使用全-轨道-增强平台

Camille Garcia1, Nina A Khristenko2, TingTing Fu1

  • 1Institut Pasteur, Université Paris Cite, CNRS UAR2024, 26-28 Rue du Docteur Roux, 75724 Cedex 15 Paris, France.

Journal of the American Society for Mass Spectrometry
|November 6, 2025
PubMed
概括

欧姆尼特拉普-轨道特拉普-增强器 (OOB) 平台增强了自上而下的质谱 (MS) 用于全面的蛋白质分析. 它使用电子捕获解离 (ECD) 实现了抗体光链的高序列覆盖,为蛋白质组学提供了一个强大的新工具.

关键词:
在ECD中,我们可以使用ECD.这是FTMS助推器.吸收模式 里埃转换 吸收模式电子捕获解离 解离mAbAb 在线播放这是一种单克隆抗体.

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