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Updated: May 5, 2026

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将细胞透的多二硫化物移植到感兴趣的基质:为无痕传递提供动态共价生物结合

Michael Cognet1,2, Giacomo Renno1,2, Filipe Coelho1,2

  • 1Department of Organic Chemistry, University of Geneva, Geneva, Switzerland.

Angewandte Chemie (International ed. in English)
|November 6, 2025
PubMed
概括

新的细胞透多二硫化物 (CPD) 能够在低蛋白度下实现无痕迹的醇介导吸收 (TMU). 这一突破克服了以前的局限性,使TMU成为生物研究的实用工具.

关键词:
生物结合的生物结合细胞吸收的时间动态共价化学 动态共价化学聚合物化学 聚合物化学提供蛋白质的蛋白质输送.

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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