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Updated: Jan 12, 2026

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
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Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib

Published on: June 26, 2019

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埃诺泽提尼布是一种选择性,穿透大脑的EGFR抑制剂,用于治疗EGFR Exon 20和非典型突变的非小细胞肺癌

Melissa R Junttila1, Claire E Repellin1, Sumeet Salaniwal1

  • 1ORIC Pharmaceuticals, Inc., South San Francisco, CA, United States.

Cancer research
|November 6, 2025
PubMed
概括

埃诺韦丁尼布有效地向非小细胞肺癌 (NSCLC) 的EGFR外基子20插入,显示出显著的瘤回归和大脑转移的完整反应. 这种药物为患有这些难以治疗的突变的NSCLC患者提供了有前途的新疗法.

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