对视野进展的方法的比较 眼睛 中央视野缺陷的眼睛
Takashi Nishida1, Robert N Weinreb1, Evan Walker1
1Hamilton Glaucoma Center, Shiley Eye Institute, and the Viterbi Family Department of Ophthalmology, University of California San Diego, La Jolla, CA, USA.
Translational vision science & technology
|November 6, 2025
概括
10-2视野 (VF) 测试检测到更多的中心VF进展在绿眼病患者比24-2 VF测试. 只依靠24-2 VF测试可能会低估疾病的进展.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 视觉现场测试 视觉现场测试
背景情况:
- 玻璃眼是全球不可逆转的失明的主要原因.
- 视野 (VF) 缺陷是绿眼病进展的关键指标.
- 精确监测VF进展是及时干预的关键.
研究的目的:
- 评估不同标准之间的一致性,以检测中部VF缺陷的眼睛视野 (VF) 进展.
- 用模拟数据集评估各种VF进展检测方法的性能.
主要方法:
- 分析了来自197名初级开角青光眼患者的282只眼睛,并进行了至少两年的随访.
- 包括多种进展检测方法:10-2和24-2VF测试,点向线性回归 (PLR),平均偏差 (MD) 和平均总偏差 (MTD).
- 构建模拟数据集,有或没有眼性变化,以评估方法性能.
主要成果:
- 10-2 VF测试检测到中心进展的频率比24-2 VF测试更高.
- 不同的进展监测方法之间的一致性低至中等.
- 模拟分析表明,10-2 VF MD在各种特异性级别中表现出最高的性能.
结论:
- 目前用于监测中心VF进展的方法显示有限的协议.
- 与24-2 VF测试相比,10-2 VF测试在检测中心进展方面更为敏感.
- 建议将10-2 VF测试与24-2 VF测试相结合,以避免低估中心VF进展.
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