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Updated: Jan 12, 2026

Mucin Agarose Gel Electrophoresis: Western Blotting for High-molecular-weight Glycoproteins
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素5ac通过前体细胞的表观遗传重编程来调节与癌症相关的纤维细胞异质性

Rachel J Kehrberg1, Namita Bhyravbhatla1, Zahraa W Alsafwani1

  • 1Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska, United States.

American journal of physiology. Cell physiology
|November 6, 2025
PubMed
概括

在胰腺癌中,Muc5ac驱动前体细胞,如脂肪衍生的介质干细胞,成为癌症相关纤维细胞 (CAF). 这项研究定义了前体细胞对CAF异质性的贡献,为胰腺癌治疗提供了新的点.

关键词:
在CAF的异质性.在Muc5ac中使用.表观遗传学是指表观遗传学.胰腺癌是一种癌症.肌肉干支 (Stroma) 是一种干支.

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