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Updated: Jan 12, 2026

Fluorescence-Based Detection of FEN1 Nuclease Activity and Screening of Small-Molecule Inhibitors
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Published on: June 27, 2025

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揭示了FERONIA受体激酶介导的细胞机制与小分子抑制剂

Mengze Sun1, Baiyan Lu2, Ying Yang2

  • 1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology, College of Chemistry and Molecular Engineering, Synthetic and Functional Biomolecules Center, and Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Peking University, Beijing 100871, China.

Proceedings of the National Academy of Sciences of the United States of America
|November 6, 2025
PubMed
概括

研究人员开发了新型抑制剂费罗维辛 (FRV),以研究FERONIA (FER) 受体激酶. 通过FRV发现了一个新的机制,其中RALF1-FER信号通过H+-ATPase抑制来调节根细胞扩张.

关键词:
费罗尼亚 (FERONIA) 是一个一个RALF1一个RALF1.激酶激酶的作用是什么小分子抑制剂小分子抑制剂

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