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在轨道成像质量和分期甲状腺相关眼科医症方面,FOCUS-MUSE DWI在MUSE和FOCUS DWI的表现优于MUSE和FOCUS

Lu Chen¹, Song Gao¹, Quan Yuan²

¹Department of Radiology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

Insights into imaging

|November 6, 2025

概括

与其他方法相比,视野优化和受约束的未扭曲的单拍多重感度编码 (FOCUS-MUSE) 扩散加权成像 (DWI) 为甲状腺相关眼科医症 (TAO) 提供了优越的轨道成像质量和分期性能. 这种先进的DWI技术被推用于TAO患者评估.

科学领域:

眼科医生眼科眼科
放射学放射学是一门学科.
医疗成像医学成像

背景情况:

甲状腺相关的眼科医疗 (TAO) 需要准确的成像来诊断和分期.
扩散权重成像 (DWI) 是评估TAO的关键技术,但图像质量和性能在不同的序列中有所不同.
优化DWI技术对于改善TAO轨道变化的评估至关重要.

研究的目的:

为了比较三个DWI技术的轨道成像质量和分阶段性能:视野优化和受约束的无扭曲单射 (FOCUS),多重感应编码 (MUSE) 和FOCUS-MUSE.
评估这些DWI序列的诊断性能,以区分活性与非活性TAO.

主要方法:

67名TAO患者使用FOCUS,MUSE和FOCUS-MUSEDWI进行了轨道成像.
图像质量被定性评估 (工件,扭曲,整体质量,边界清晰度) 和定量评估 (GDR,SNR,ADC,nADC).
在活跃和不活跃的TAO组之间比较了眼外肌肉 (EOMs) 的正常化明显扩散系数 (nADC) 值,以评估分期性能.

主要成果:

与MUSE和FOCUS DWI相比,FOCUS-MUSE DWI显示出明显更少的文物和几何扭曲,更高的图像质量,更强的边界清晰度,更高的SNR和更低的GDR (p <0.05).
虽然ADC值不同,但正常化的ADC (nADC) 值在序列之间没有显著差异,除了高级EOM.
活跃的TAO患者在所有三种DWI技术中表现出比不活跃的患者更高的nADC值 (p < 0.05).
在分期活性TAO方面,FOCUS-MUSE DWI实现了最高的诊断性能 (AUC: 0.890;灵敏度: 84.8%;特异性: 77.3%),超过了MUSE和FOCUS DWI (p < 0.001).

结论:

与MUSE和FOCUS DWI相比,FOCUS-MUSE DWI为TAO提供了优越的图像质量和增强的分期性能.
来自FOCUS-MUSE DWI的正常化明显扩散系数 (nADC) 是评估TAO活动的有价值指标.
建议使用FOCUS-MUSE DWI进行TAO患者的常规临床评估.

关键词:

扩散权重成像技术的使用.图像质量图像质量磁共振成像技术磁共振成像技术进行分期,分期.甲状腺相关的眼睛疾病.

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