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Updated: Jan 12, 2026

Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction
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Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction

Published on: October 6, 2022

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可编程的aptamer-药物联合体:扩大针对性治疗的自动化和模块化平台

Haoji Wang1, Thulasiram Bathini1, Shangjiu Hu1

  • 1Institute of Molecular Medicine (IMM), Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine, Renji Hospital, School of Medicine, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, China.

Current protocols
|November 6, 2025
PubMed
概括

这项研究介绍了一种模块化,自动化的方法,用于创建阿普坦尔-药物合物 (ApDC). 这一新策略允许精确的药物加载和部位特异性,改善向癌症治疗.

关键词:
这就是PApDCs.这是一种寡核化物.胺酸的化学成分可编程的阿帕特默药物合物固相合成的固相合成方法有针对性的药物输送.

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Drug Discovery: Overview

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