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Updated: Jan 12, 2026

Induction and Testing of Hypoxia in Cell Culture
07:01

Induction and Testing of Hypoxia in Cell Culture

Published on: August 12, 2011

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cPLA2α驱动的Cox-2/PGE2轴促进Jurkat T细胞中缺氧诱导的衰老

Jae-Ha Jung1, Yeseul Yang2, Yongbaek Kim3

  • 1Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea; BK 21 FOUR Program for Future Veterinary Medicine Leading Education and Research Center, College of Veterinary Medicine, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, South Korea.

Biochemical and biophysical research communications
|November 6, 2025
PubMed
概括

缺氧通过cPLA2α激活促进T细胞衰老,增加脂质积累和细胞循环停止. 抑制cPLA2α可能通过恢复T细胞功能来增强抗癌免疫疗法.

关键词:
氧气过低是因为缺氧.免疫治疗是一种免疫疗法.衰老是一种衰老.一个T细胞细胞.瘤微环境是一个微环境.

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