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PDL1-inhi.predictor:一个双层机器学习框架,用于预测和优先考虑PDL1抑制剂

Huiyan Ying1, Junting Liu2, Weikaixin Kong3

  • 1Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.

Bioorganic chemistry
|November 6, 2025
PubMed
概括

机器学习模型加速发现小分子抑制剂的发现,这些抑制剂针对癌症治疗的编程细胞死亡蛋白1合物1 (PDL1) 分解. 两个经过验证的化合物显示出强大的PDL1抑制,为药物开发提供了有前途的化合物.

关键词:
活动预测活动预测.亲和关系估计的估计.机器学习 机器学习PDL1 抑制剂的使用在PDL1-inhi.Predictor网络服务器上.下结构的图案是次结构的图案.

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