人格障碍的全球流行病学:系统性审查和元回归
Jamileh Shadid1, Alize J Ferrari1, Bo Bach2
1School of Public Health, The University of Queensland, Herston, QLD, Australia; Queensland Centre for Mental Health Research, Wacol, QLD, Australia; Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
人格障碍在全球范围内很常见,影响了超过4%的人,并与明显更高的死亡率有关. 这种心理健康状况随着时间的推移显示出中度的诊断稳定性,突出显示了其持续的影响.
科学领域:
- 流行病学 流行病学
- 全球心理健康全球心理健康
- 精神病学是一个精神病学.
背景情况:
- 人格障碍是一种普遍的精神障碍,在全球卫生估计中经常被忽视.
- 现有的全球心理健康数据缺乏全面量化人格障碍患病率,死亡率和诊断稳定性的数据.
- 这项研究解决了这些缺口,以告知疾病模型的未来负担.
研究的目的:
- 系统地审查和对人格障碍的全球流行率,死亡率和诊断稳定性的人口代表性数据进行元回归.
- 提供个性障碍流行病学的全面综合.
- 为未来对人格障碍的全球估计和政策反应提供信息.
主要方法:
- 根据PRISMA和GATHER指南对基于人口的调查进行系统审查和元回归.
- 包括在代表性样本上使用DSM或ICD标准的横截面或纵向研究.
- 排除使用自我报告工具或非代表性样本的研究;在PubMed,Embase和PsycINFO (1980-2024) 中进行系统搜索.
主要成果:
- 确定了28个国家的60项研究,包括超过139,000名患者的流行率和392,000人的死亡率.
- 任何个性障碍的综合流行率在低收入/中等收入国家为4.1%,在高收入国家为5.2%.
- 人格障碍与死亡率升高有关 (SMRs 1.8-4.7) 并显示出中度诊断稳定性.
结论:
- 人格障碍是与过早死亡相关的常见疾病,具有中等的诊断稳定性.
- 尽管有影响,但人格障碍仍然被排除在全球主要疾病研究负担之外.
- 这种全面的流行病学综合分析为改善全球估计和政策干预提供了基础.
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