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审查营养参考值证据的质量
Sumati Bajaj1, Marco Springmann2
1Institute for Global Health, University College London, London, UK.
The Lancet. Planetary health
|November 6, 2025
概括
营养参考值 (NRV) 的准确性受到证据薄弱的限制. 由于过时的研究和稀缺的数据,目前的微量营养素NRV应谨慎使用,需要改进的研究方法.
科学领域:
- 营养科学 营养科学
- 饮食评估 饮食评估
- 公共卫生 营养 公共卫生 营养
背景情况:
- 营养参考值 (NRV) 对于饮食指南和评估营养充足度至关重要.
- NRV的可靠性取决于支持它们的科学证据的质量.
- 之前对NRV的评估没有全面评估不同监管机构的证据基础.
研究的目的:
- 对美国医学研究所 (IOM) 和欧洲食品安全局 (EFSA) 建立的21种微量营养素NRV的证据进行批判性评估.
- 评估用于建立这些NRV的方法质量,数据新性和研究特征.
- 提出建议,以加强未来NRV发展的证据基础.
主要方法:
- 对国际移民组织 (IOM) 和欧洲食品安全局对21种微量营养素的NRV使用的证据进行系统审查.
- 对方法方法,样本大小,出版日期和研究持续时间的分析.
- 开发一个分类系统来评价基础证据的质量.
主要成果:
- 发现了重要的局限性,包括依赖小型,过时的研究和间接证据 (例如平衡研究).
- 欧洲食品安全局 (EFSA) 使用的数据比医学研究所 (IOM) 更近,但证据质量差距仍然存在.
- 两个组织的证据库中普遍存在稀缺的实验数据和间接方法.
结论:
- 目前的NRV由于支持证据的质量而存在局限性,因此应谨慎解释.
- 建议包括优先考虑直接的,以充分性为重点的研究,大规模的长期研究和元分析.
- 对于准确的营养评估,对当前NRVs周围的不确定性进行明确的沟通至关重要.
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