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Updated: Jan 12, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

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MARCH8介导的无处可见性调节了抗病毒蛋白IFITM3的表达

Liang Wei1, Fei Zhao1, Xiaoman Liu1

  • 1Key Laboratory of Pathogen Infection Prevention and Control (Ministry of Education), State Key Laboratory of Respiratory Health and Multimorbidity, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China; NHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology and Center for AIDS Research, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China.

The Journal of biological chemistry
|November 6, 2025
PubMed
概括

膜相关的RING-CH 8 (MARCH8) E3结合酶针对抗病毒蛋白IFITM3进行降解. 这一过程增强了病毒的进入,揭示了天生的免疫调节的新机制.

关键词:
E3 结合酶的使用如果FITM3是IFITM3,那么它是什么?国际货币基金组织 IFN IFN3月8日 时间:无处不在的化病毒感染 病毒感染

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