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Updated: Jan 12, 2026

In Vitro Analysis of E3 Ubiquitin Ligase Function
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结构基础为E3无素结合酶UHRF1结合于核体核心粒子和素H3无素化

Reia Shikimachi1, Shun Matsuzawa1, Hiroki Onoda2

  • 1Structural Biology Laboratory, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa, Japan.

The Journal of biological chemistry
|November 6, 2025
PubMed
概括

与植物主体和RING指域1 (UHRF1) 相似的乌比奎丁通过一种新的相互作用结合了核体. 这种相互作用是基因素H3无化和DNA甲基化维护的关键.

关键词:
通过DNA甲基化.在UHRF1中,UHRF1是UHRF1.低温电磁波冷却器 (Cryo-EM) 是一个非常好的方法.核的重建 核的重建结构生物学结构生物学无处不在的化

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