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脉冲场切除与大功率短期切除在心房动:一个系统和元分析
Uzair Nisar Malik1, Tuba Abeer Hashmi, Priya Bai
1From the Department of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.
Cardiology in review
|November 6, 2025
概括
脉冲场移除 (PFA) 显示出与高功率短期 (HPSD) 射频移除在心房 (AF) 治疗中的效果相似. PFA 提供了更好的安全性和程序效率,使其成为 AF 切除的有希望的选择.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 电子生理学 电子生理学
背景情况:
- 心房动 (AF) 是一种常见的心律失常症,需要有效的废除策略.
- 脉冲场切除 (PFA) 和高功率短时间 (HPSD) 射频切除是AF治疗的先进技术.
- 直接比较PFA和HPSD对于指导临床实践至关重要.
研究的目的:
- 在AF患者中,系统地比较PFA与HPSD射频废除的疗效,安全性和程序特征.
- 进行可用的随机对照试验和观察性研究的元分析.
- 评估与每种废除方式相关的长期结果和并发症率.
主要方法:
- 对12项包括2000多名患者在内的研究进行了系统性审查和元分析.
- 搜索了PubMed和其他数据库到2025年7月.
- 提取了基线特征,程序细节,临床结果和并发症的数据;评估了偏差风险;用于统计聚合的随机效应模型.
主要成果:
- 在PFA (85.3%) 和HPSD (83.2%) 之间,类似的12个月无AF率.
- 在PFA中,并发症的发生率显著降低,包括心脏吸管,神经损伤和食道损伤.
- PFA在程序效率方面表现出优势,减少了光学时间,能源输送和调试要求.
结论:
- 在治疗心房动方面,PFA的疗效与HPSD的射频除疗效相当.
- 与HPSD相比,PFA具有更高的安全性和更高的程序效率.
- PFA是治疗心房动患者的有利和有效的废除方式.
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