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全球各地的人口中痴呆的发病率
Ashleigh S Vella1, Susanne Roehr1,2, Perminder S Sachdev1
1Centre for Healthy Brain Ageing, Discipline of Psychiatry & Mental Health, School of Clinical Medicine, University of New South Wales, Sydney, Australia.
Current opinion in psychiatry
|November 6, 2025
概括
全球痴呆发病率估计不准确,原因是低收入和中等收入国家 (LMICs) 和少数民族的代表人数不足. 更多样化,更具代表性的数据对于准确的痴呆风险评估和有效的公共卫生战略至关重要.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 人口统计学 人口统计学
背景情况:
- 全球痴呆发病率估计因低收入和中等收入国家 (LMICs) 和少数群体的代表性不足和诊断不足而显著扭曲.
- 现有的研究不平等性阻碍了准确的全球痴呆发病率评估.
- 识别和解决这些研究缺口对于可靠的全球痴呆症统计数据至关重要.
研究的目的:
- 综合了解全球痴呆症发病率的最新进展.
- 识别和解决影响痴呆症发病率估计的研究不平等问题,特别是在LMIC和少数民族中.
- 强调数据收集多样性的重要性,以实现更可靠的全球痴呆症估计.
主要方法:
- 对全球痴呆症发病率的最新文献进行系统审查.
- 在痴呆症流行病学中分析数据缺口和研究不平等.
- 识别改善数据质量和表现的机会.
主要成果:
- 痴呆症发病率在地理位置上有所不同,在欧洲和美国的趋势下降,但在一些亚洲国家增加趋势.
- 全球估计因在LMIC和少数群体中代表性不足和诊断不足而出现偏差.
- 风险因子的影响,如阿波利波蛋白Eε4,显示出人群特异性的变化,需要进行特定国家的分析.
结论:
- 迫切需要高质量,纵向,具有代表性的数据集,特别是来自研究不足的LMIC和各种民族种族群体.
- 投资于当地领导的队列研究,文化敏感的评估和公平的合作是至关重要的.
- 方法透明度和协调是提高发病率准确度和指导特定人口的公共卫生政策的关键.
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