NLRP3的药理学调制3:从治疗个性化到创新药物

Giulia Zudeh1, Sara Sossai2, Jacopo Angelini3

  • 1Department of Translational and Advanced Diagnostics, Institute for Maternal and Child Health I.R.C.C.S. Burlo Garofolo, 34137 Trieste, Italy.

概括

核酸结合域,含有白氨酸丰富的家族,含有氨酸域-3 (NLRP3) 炎症酶对炎症至关重要. 在炎症性疾病中,NLRP3促进剂甲基化可能预测葡萄糖皮质激素治疗反应.

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