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Updated: Jan 12, 2026

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
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Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy

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依赖MYC的lncRNA MB3通过通过HMGN5调节TGF-β通路来抑制第三组中枢细胞瘤中细胞灭亡

Alessia Grandioso1,2, Paolo Tollis3, Francesca Romana Pellegrini2

  • 1Department of Biology and Biotechnologies Charles Darwin, Sapienza University of Rome, Rome, Italy.

Cell death & disease
|November 6, 2025
PubMed
概括

一种新型的长非编码RNA, lncMB3,通过抑制亡来驱动侵袭性的儿科髓母细胞瘤 (MB). 针对 lncMB3 为这种具有挑战性的脑瘤提供了一个有前途的治疗策略.

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