在机械通风ICU患者中对PTSD症状发展进行了纵向潜伏类增长分析
Yunting Li1, Jiabi Zhang2, Chen Wei1
1Department of Neurosurgery, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, China.
Scientific reports
|November 6, 2025
概括
重症监护室 (ICU) 患者在机械通风后发展出各种创伤后应激障碍 (PTSD) 轨迹. 低教育和长时间住院预测更糟糕的结果,需要对有风险的个体进行早期干预.
科学领域:
- 关键护理医学 关键护理医学
- 精神病学是一个精神病学.
- 纵向健康研究 纵向健康研究
背景情况:
- 重症监护室 (ICU) 患者患创伤后应激障碍 (PTSD) 的风险很高.
- 在ICU的过程性疼痛和沟通问题可以引发压力,恐惧和无助感,导致PTSD.
- 现有的关于ICU幸存者的PTSD研究是有限的,特别是追踪恢复的纵向研究.
研究的目的:
- 在机械通风ICU患者中识别PTSD的异质发育轨迹,直至输出管术后6个月.
- 分析与不同PTSD轨迹子组相关的临床特征和风险因素.
主要方法:
- 一项前性纵向研究跟踪了中国的204名机械通风ICU患者.
- 基线评估包括人口统计,PTSD (IES-R),焦虑/抑郁 (HADS),应对,个性和社会支持.
- 创伤后应激障碍 (IES-R) 的后续评估是在输出管后的1,3个月和6个月进行的.
主要成果:
- 确定了四种不同的PTSD轨迹:高风险恶化 (6.9%),高风险改善 (27.2%),中等风险维持 (14.3%) 和低风险改善 (51.6%).
- 教育水平较低,住院时间长,ICU退院时间延迟,以及基线焦虑独立预测了不良的PTSD轨迹.
- 在这些患者中,PTSD发展存在显著的异质性.
结论:
- 机械通风的ICU患者表现出不同的PTSD恢复途径.
- 对高风险患者 (例如,低学历或长时间住院患者) 的早期诊断和干预对于改善结果至关重要.
- 建议提供有针对性的心理支持,以减轻风险人群的长期心理健康负担.
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