强烈的体育训练会诱导运动员释放NET
Joanna Orysiak1, Jitendra Kumar Tripathi2, Klaudia Brodaczewska3
1Central Institute for Labour Protection-National Research Institute, Warsaw, Poland. joanna.orysiak@ciop.pl.
强烈的体育训练显著增加了中性粒细胞外细胞陷 (NETs) 在冰球运动员中的释放. 轻微的上呼吸道感染 (URTI) 在训练期间没有进一步影响NET释放.
科学领域:
- 运动医学 运动医学
- 免疫学 免疫学 免疫学
- 运动生理学 运动生理学
背景情况:
- 强烈的体育训练会影响运动员的免疫功能.
- 中性细胞外细胞陷 (NETs) 在免疫反应中发挥作用.
- 了解在训练期间释放的NET对于运动员健康至关重要.
研究的目的:
- 调查强度体育训练对NETs释放的影响.
- 为了比较URTI-free与URTI-prone运动员中的NETs释放.
- 评估轻度URTI在培训期间对NET释放的影响.
主要方法:
- 在国家训练营期间监测了16名男子冰球运动员.
- 训练前和训练后收集的血液样本,检测免疫和内分泌标记物.
- 测量了肌酸激酶,白细胞,皮质醇,IgA,CRP和NETs的释放.
- 通过问卷追踪上呼吸道感染 (URTI) 的发生情况.
主要成果:
- 培训后CK活性和尿酸水平显著增加.
- 在所有运动员训练后,NETs的释放显著增加.
- 在无URTI和易患URTI组之间,免疫/内分泌标志物没有显著差异.
- 轻度URTI在训练营期间没有显著影响NETs释放.
结论:
- 仅仅是强烈的体育训练可以提高运动员中NETs的释放.
- 运动员对URTI的敏感性并没有改变训练诱导的NETs释放.
- 需要进一步研究培训诱导的NET的长期影响.
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