使用肺部区域沉积模型作为局部作用口服吸入药物产品的模型整合证据

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Updated: Jan 12, 2026

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
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Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models

Published on: November 11, 2020

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Ross L Walenga1, Steven G Chopski2, Jae H Lee2

  • 1Division of Quantitative Methods and Modeling, Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U. S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA. Ross.Walenga@fda.hhs.gov.

Pharmaceutical research
|November 6, 2025
PubMed
概括

肺部区域沉积建模 (RDM) 提供了一个解决方案,用于评估口服吸入药物产品 (OIDPs) 中的药物输送. 这种方法有助于了解特定区域的肺部输送,促进通用产品的开发和改善患者的获取.

关键词:
计算流体动力学的流体动力学.模型可信度 模型可信度模型整合证据模型整合证据口服吸入的药物产品是口服吸入的药物产品.区域存款建模 区域存款建模

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