肺瘤血栓性微血管病二次到乳外帕吉特病:一个尸检案例报告
Ryosuke Mochizuki1, Rikako Miyazaki1, Shoko Nakatani1
1Department of Dermatology, Hyogo Cancer Center, Akashi, Japan.
The Journal of dermatology
|November 6, 2025
概括
肺瘤血栓性微血管病变 (PTTM) 是癌症的一种罕见并发症. 这一案例突出了PTTM二次到乳外Paget的特点.
科学领域:
- 在瘤学瘤学.
- 肺部医学 肺部医学
- 病理学 病理学 病理学
背景情况:
- 肺瘤血栓性微血管病变 (PTTM) 是转移性恶性病的罕见致命并发症.
- 它呈现出快速呼吸不全和严重的肺高血压.
研究的目的:
- 描述一种罕见的PTTM病例,是乳腺外帕杰特病 (EMPD) 的次要病例.
- 为了突出皮肤恶性瘤中不常见的PTTM呈现.
主要方法:
- 一个75岁的老人患有转移性EMPD的病例报告.
- 基于症状,成像和肺高血压的PTTM临床诊断.
- 启动意马提尼布治疗.
- 尸检后的验证证实了这一点.
主要成果:
- 患者在化疗前出现了急性,严重的呼吸障碍.
- 对PTTM进行了临床诊断.
- 尽管服用伊马替尼布,但病情恶化,患者在5天内死亡.
- 尸检证实了肺血管中的微观瘤栓塞和纤维素血栓.
结论:
- 由皮肤恶性瘤引起的PTTM非常罕见.
- 这一案例说明了一个不常见的呈现 PTTM 二次到 EMPD.
- 早期识别和治疗PTTM至关重要,尽管结果仍然很差.
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