转移性前列腺癌的发病率上升,但种族差距正在缩小
Hanna Zurl1,2,3, Zhiyu Qian2,3, Klara K Pohl1,2,3
1Department of Urology, Medical University of Graz, Graz, Austria.
BMC medicine
|November 6, 2025
概括
由于黑人男性的查率更高,晚期前列腺癌 (PCa) 的种族差距缩小了,但这个群体的查下降速度更快,引发了对未来差异的担忧.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 健康差异 在健康上的差异
背景情况:
- 包括查在内的前列腺癌 (PCa) 护理中的种族差异是一个重大问题.
- 最近的兴趣集中在了解和解决这些差异上,特别是在风险适应的查策略中.
研究的目的:
- 通过种族来研究转移性PCa发病率的趋势.
- 为了将这些趋势与前列腺特异性抗原 (PSA) 查建议和吸收的变化联系起来.
主要方法:
- 用SEER数据分析转移性PCa发病率数据,按种族 (2005-2021) 划分.
- 使用BRFSS数据分析PSA查趋势 (2012-2020年).
- 用通用线性模型来评估非西班牙裔黑人 (NHB) 与非西班牙裔白人 (NHW) 男人的种族发病率比率和查几率比率.
主要成果:
- 从2005年到2021年,转移性PCa的发病率在NHB和NHW男性中增加.
- 发病率的种族差距缩小,NHB与NHW发病率比率从2.6下降到2.1.
- 从2012年到2020年,PSA查在两个群体中都下降了,NHB男性的下降幅度更大,到2020年没有显著差异.
结论:
- 在研究期间,转移性PCa的种族差异缩小了,与整体发病率的增加相吻合.
- 2010年代初,NHB男性的PSA查率较高,可能有助于缩小差距.
- 在NHB男性中查的快速下降引发了人们对未来种族差异可能复苏的担忧.
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