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Isolation of Leukocytes from Human Breast Milk for Use in an Antibody-dependent Cellular Phagocytosis Assay of HIV Targets
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基于生理学的药物动力学模型与临床哺乳期研究相结合,以确定人类母乳中的多拉维林度

Lena van der Wekken-Pas1, David Burger1, Rick Greupink1

  • 1Radboud university medical center, department of Pharmacy, Pharmacology and Toxicology, Radboud Institute for Medical Innovations (RIMI), Nijmegen, the Netherlands.

British journal of clinical pharmacology
|November 7, 2025
PubMed
概括

用生理学基础的药理动力学 (PBPK) 建模和临床研究来评估多拉维林转移到母乳中. 预计婴儿通过母乳接触多拉维林不会危害婴儿.

关键词:
艾滋病病毒 艾滋病病毒 艾滋病病毒在PBPK模型中,临床哺乳研究 临床哺乳研究多拉维林 (Doravirine) 是一种人类母乳人类母乳

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