刺的纸质电化学可穿戴设备用于伤口pH值监测
Laura Belcastro1, Luca Fiore1,2, Hima Zafar3
1Department of Chemical Science and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, Rome 00133, Italy. fabiana.arduini@uniroma2.it.
Lab on a chip
|November 7, 2025
概括
研究人员开发了一种新的可穿戴设备,使用纸上嵌的线程用于慢性伤口的电化学pH监测. 这种微流体线程/纸质分析装置 (μTPAD) 提供了一种可靠且易于使用的伤口评估方法.
科学领域:
- 电化学 电化学 电化学
- 材料科学 材料科学 材料科学
- 生物医学工程 生物医学工程
背景情况:
- 慢性伤口需要持续监测以获得有效的治疗.
- 目前的pH监测方法可能具有侵入性或缺乏可移植性.
- 基于纸质的分析设备提供低成本,一次性传感平台.
研究的目的:
- 开发和验证第一个电化学微流体线程/纸质分析装置 (μTPAD).
- 使用可穿戴系统,使慢性伤口的潜在度pH值监测成为可能.
- 与实验室标准相比,证明设备的可靠性和准确性.
主要方法:
- 通过在过纸上刺导电线进行μTPAD的制造.
- 用氧化修改工作电极,用于质子传感.
- 与便携式电源控制器,蓝牙和智能手机应用程序进行数据读取的集成.
- 测试用于在4-8的范围内的电位计pH值监测.
主要成果:
- TPAD的灵敏度为0.056 ± 0.002 V pH-1和可重复性 (RSD%) 为8%.
- 可穿戴设备准确地监测了慢性伤口液中的pH值,与实验室pH值计相对应得很好.
- 通过使用一次性μ线程纸片,实现了多次分析的设计.
结论:
- 开发的μTPAD代表了用于慢性伤口pH监测的新,可穿戴和可靠的平台.
- 刺和基于纸张的技术的结合为低成本的生物传感提供了一个有希望的方法.
- 这项技术可促进伤口状况的可访问和持续监测,有助于临床决策.
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