在中死亡性肠炎的流行,分子检测和组织病理学分析
Amir Bashir Kouchey1, Showkat Ahmad Shah1, Majid Shafi1
1Division of Veterinary Pathology, FVSc & AH, Shuhama, SKUAST Kashmir, Srinagar, India.
Open veterinary journal
|November 7, 2025
概括
肉中死肠炎 (NE) 是由Clostridium perfringens引起的,会影响直肠,特别是在22-28天大的鸟类中. 这项研究在95个疑似病例中,在37个病例中证实了NE,突出了它对家禽业的影响.
科学领域:
- 兽医病理学 兽医病理学
- 禽畜科学 禽畜科学 禽畜科学
- 微生物学 微生物学
背景情况:
- 全球 brojiler行业的扩张带来了Clostridium perfringens诱导的死肠炎 (NE) 的挑战.
- 禁止使用抗微生物生长促进剂增加了NE在家禽养殖中的经济影响.
- 了解NE患病率和病理学对于肉疾病管理至关重要.
研究的目的:
- 为了确定在印度克什米尔的肉中死肠炎 (NE) 的流行率.
- 为了研究受影响的肉中与NE相关的组织病理学变化.
- 确定Clostridium perfringens类型A作为NE的致病原体.
主要方法:
- 从怀疑NE的肉采集了95个便和肠道样本.
- 使用聚合酶链反应 (PCR) 识别A型透.
- 对受影响的肠道组织进行粗体和组织病理学检查.
主要成果:
- 在95例疑似病例中,NE在37例 (1.22%发生率) 中得到证实.
- 在22-28天的肉中观察到最高的患病率 (0.73%).
- 严重的病变包括骨变薄,气球膨胀和焦点黑色斑点; 组织病理学揭示了粘膜 necrosis,皮脱皮和炎症.
结论:
- 在克什米尔,疑似肉的37.1%被证实是Clostridium perfringens诱导的NE.
- 阴是主要受影响的部位,观察到具有特征的病理变化.
- 年龄组22-28天的患病率最高,这表明NE易感性的关键时期.
关键词:
肉牛肉是什么意思克洛斯特里 (Clostridium perfringensens) 是一种有毒的植物.历史形态学 历史形态学死亡性肠炎 (necrotic enteritis) 是一个疾病.更多相关视频
06:57Loop-mediated Isothermal Amplification LAMP Assays for the Species-specific Detection of Eimeria that Infect Chickens
Published on: February 20, 2015
27.5K
09:21A Ligated Intestinal Loop Model in Anesthetized Specific Pathogen Free Chickens to Study Clostridium Perfringens Virulence
Published on: October 11, 2018
9.9K
相关概念视频
Investigation of Disease Outbreaks
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Rapid Identification of Pathogens
MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...
Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
