皮肤注射前的消毒剂:世卫组织对洗的建议,而不是基于酒精的消毒剂,是否达到同样的效果?
Torsten Koburger-Janssen1, Paula Zwicker2,3, Ojan Assadian4
1Hygiene Nord GmbH, Greifswald, Germany.
GMS hygiene and infection control
|November 7, 2025
概括
使用肥和水的皮肤消毒剂与以酒精为基础的解决方案一样有效,可以在注射前减少微生物负载. 这项研究发现,肥和酒精之间的细菌减少没有显著差异,这表明肥是可行的替代品.
科学领域:
- 微生物学 微生物学
- 皮肤病学 皮肤病学
- 感染控制 感染控制
背景情况:
- 在注射之前,皮肤消毒非常重要,以最大限度地降低来自居民和短暂植物群的感染风险.
- 世界卫生组织 (WHO) 建议用肥和水可能足够,质疑基于酒精的消毒剂的必要性.
- 存在有限的证据来比较酒精与肥在注射前皮肤制备方面的疗效.
研究的目的:
- 为了比较肥和基于酒精的溶液在减少皮肤微生物负荷方面的有效性.
- 在侵入性手术之前评估不同皮肤消毒方法的有效性.
主要方法:
- 23名志愿者用液体洗乳液 (肥) 或-2-醇 (酒精) 涂抹在他们的上臂上.
- 微生物样本是在特定的擦拭和干燥时间后使用无菌抹布收集的.
- 细菌悬浮被涂在 agar 上进行分析.
主要成果:
- 肥和酒精都表现出类似的细菌负载减少 (约为1log).
- 两种方法之间或试验变异之间没有观察到有效性的显著差异.
- 相当的细菌减少表明,这两种消毒方法的有效性相似.
结论:
- 肥和基于酒精的溶液在减少皮肤微生物负载方面同样有效.
- 虽然这两种方法在法律上都是可以接受的,但当没有使用活疫苗时,基于酒精的消毒剂提供了用户友好性.
- 臂部皮肤殖民密度较低可能有助于观察到的同等效率.
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