相关实验视频
Updated: Jan 12, 2026

03:36
Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
747
在食道恶性病变后出现的副发性中枢和外围脱线:一个病例报告
Farheen S Bhanu1, Rithvik Ramesh1, Lakshmi Narasimhan Ranganathan1
1Neurology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cureus
|November 7, 2025
概括
一个罕见的同时发生中枢神经系统和外周神经系统脱髓化的病例与未被诊断的食道癌症有关. 早期癌症查对于对典型治疗无反应的脱髓化综合征至关重要.
科学领域:
- 神经学 神经学
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
背景情况:
- 脱线性综合征可以呈现出各种神经系统缺陷.
- 麻性综合征经常表现为神经系统症状,这是潜在恶性瘤的次要原因.
- 同时的中枢神经系统和外周神经系统的参与是一种不常见的表现.
研究的目的:
- 报告同时发生的中央和外周脱髓化病例作为瘤性表现.
- 强调在耐火性脱髓化疾病中调查潜在恶性瘤的重要性.
- 突出在这种情况下的诊断挑战和管理考虑.
主要方法:
- 一个60多岁的男性患有亚急性神经缺陷的临床表现.
- 诊断工作包括神经传导研究,MRI,CSF分析和PET-CT.
- 胸腔食道恶性瘤的组织病理学确认.
- 对免疫治疗 (静脉注射免疫球蛋白) 的反应评估.
主要成果:
- 患者表现出亚急性下肢虚弱,麻木和尿路滞留.
- 神经传导研究表明了脱髓化参数;MRI显示中枢神经系统病变.
- 脑脊液分析显示了白细胞学解离.
- 通过PET-CT扫描检测出胸腔食道癌症,从而诊断出瘤性脱髓化.
- 症状进展,尽管静脉注射免疫球蛋白治疗.
结论:
- 同时发生的中央和外围脱髓化可能是瘤现象.
- 恶性查对患有脱髓化综合征的患者至关重要,这些患者对标准免疫疗法没有反应.
- 癌症的早期检测对于潜在地改善神经神经瘤神经系统疾病的结果至关重要.
相关概念视频
Barrett Esophagus-II: Clinical Manifestations and Management
748
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
748
Esophageal Perforation-II: Clinical Manifestations and Management
477
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
477
Esophageal Strictures-I: Introduction
614
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
614
Barrett Esophagus-I: Introduction
594
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
594
Esophageal Strictures-II: Clinical Features and Management
404
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
404
Esophagus
3.6K
The esophagus, a muscular conduit linking the pharynx and stomach, measures roughly 10 inches (25.4 cm) and sits behind the trachea. It remains collapsed when not swallowing. The esophagus follows a predominantly straight path through the thoracic mediastinum and enters the abdominal cavity through a diaphragmatic opening known as the esophageal hiatus.
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
3.6K

