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海伦·约瑟夫医院的三阴性乳腺癌:流行率,年龄和成像特征

Tsholofelo Zondi¹, Grace Rubin¹, Carol-Ann Benn²

¹Department of Radiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

SA journal of radiology

|November 7, 2025

概括

三重阴性乳腺癌 (TNBC) 是攻击性的,在南非很常见. 图像可能不反映其侵略性,需要提高临床警,以便早期检测.

科学领域:

在瘤学瘤学.
放射学放射学是一门学科.
病理学病理学病理学

背景情况:

三阴性乳腺癌 (TNBC) 是一种缺乏雌激素,孕激素和HER2受体的侵袭性乳腺癌亚型.
在南非,TNBC经常更早,更积极地呈现,对其特征的数据有限.

研究的目的:

在海伦约瑟夫三级医院 (HJTH) 确定TNBC的流行率.
描述TNBC的组织病理特征,诊断时的年龄,以及南非的成像模式.
调查早期出现的TNBC趋势.

主要方法:

在2021年1月至2023年12月期间诊断出280名女性乳腺癌患者的回顾性评估.
用描述性统计和千平方测试分析人口统计,成像和组织病理学数据.

主要成果:

在乳腺癌病例中,TNBC占17% (48/280).
TNBC病变的平均长度为1-5厘米,结节参与率为73%.
尽管TNBC具有攻击性生物学,但TNBC成像通常看起来是良性的;61%的乳腺癌是高等级的,TNBC显示最高的平均Ki-67指数 (52%).

结论:

在南非,乳腺癌的呈现是复杂的,瘤生物学和成像发现之间存在潜在的不一致.
调查结果提供了关于在城市公共卫生保健环境中TNBC的关键当地数据.
强调需要加强对TNBC的成像意识和临床警,在资源有限的环境中.

关键词:

基-67抗原是一种抗原.乳腺新生体的发生.早期发病的乳腺癌.流行病学流行病学图像特征的成像特性乳房学乳房学乳房学三重阴性乳腺癌是什么超声波超声波是指超声波的使用.

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