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Updated: Jan 12, 2026

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
08:52

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Published on: March 18, 2022

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氨酸通过mTORC1/LXRα介导的巨细胞重编程和rspo2/β-catenin轴抑制来减轻骨关节炎

Ke Zheng1,2, Jiebin Zhang2, Wenxiang Liu2

  • 1Department of Orthopedics, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Cartilage
|November 7, 2025
PubMed
概括

素 (Leu) 补充剂通过通过mTORC1/LXRα通路重编程巨细胞,有效治疗关节炎. 这种干预减少了软骨损伤和骨细胞的形成,为关节疾病提供了一种新的营养策略.

关键词:
在R-spondin 2中使用.氨酸 (leucine) 是一种蛋白质.巨细胞的两极分化拉帕素复合物的哺乳动物目标1/肝脏X受体α信号通路.在β-catenin信号通路中.

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