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一个iPSC衍生的模型用于大脑小血管疾病中药物查

Alessandra Granata1, Maha Al-Thani1, Mary Goodwin-Trotman1

  • 1Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
|November 7, 2025
PubMed
概括

诱导多能干细胞 (iPSCs) 创造了脑小血管疾病 (cSVD) 的新模型. MMP 抑制剂在恢复血脑屏障功能方面表现有前途,为cSVD提供了潜在的治疗策略.

关键词:
大脑小血管疾病大脑小血管疾病药物查对药物进行查.诱导多能干细胞的诱导干细胞.矩阵金属蛋白质酶是一种金属蛋白质.血管痴呆症是一种精神病.

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