胃癌患者心血管死亡风险 胃癌患者心血管死亡风险
Tian Zhang1, Lingling Guan2, Xiaomeng Xie2
1Department of Pathology, Shiyan People's Hospital of Bao'an District, Shenzhen, Guangdong, China.
PloS one
|November 7, 2025
概括
与一般人群相比,胃癌 (GC) 患者面临心血管疾病 (CVD) 死亡风险明显更高. 这种风险在年轻人中特别高,并在诊断后立即出现.
科学领域:
- 在瘤学瘤学.
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 胃癌 (GC) 是一个重要的全球健康问题.
- 心血管疾病 (CVD) 仍然是全球主要的死亡原因.
- 目前尚不完全理解GC与心血管疾病死亡风险之间的相互作用.
研究的目的:
- 量化胃癌 (GC) 患者心血管疾病 (CVD) 过度死亡风险.
- 为了比较GC患者与普通人群的心血管疾病死亡率.
主要方法:
- 基于人口的回顾性队列研究,利用SEER计划数据 (1990-2021年).
- 包括41,083名GC患者 (≥30岁) 和匹配的一般人群队列.
- 普森回归用于估计心脏病死亡率的发病率比率 (IRR).
主要成果:
- 在GC患者中,心血管疾病死亡风险增加了46% (IRR: 1.46;95% CI: 1.40-1.52).
- 在年轻患者 (30-39岁;IRR:7.69) 中观察到的相对风险最高.
- 心血管疾病死亡风险在诊断后的第一个月达到顶峰 (IRR:11.52).
结论:
- 研究结果强调了与GC相关的心血管疾病死亡风险增加.
- 支持早期心脏评估和GC患者护理中的风险分层.
- 需要通过详细的混数据进行进一步的研究.
相关概念视频
Psychoneuroimmunology: Cardiovascular Disease
376
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
376
Exercise and Cardiovascular Response
3.9K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
3.9K
Pericarditis IV: Nursing Management
304
Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
304
Coronary Artery Disease I: Introduction
863
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
863
Esophageal Varices-II: Clinical Features and Management
355
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
355
Esophageal Varices-I: Introduction
1.1K
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
1.1K


