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Updated: Jan 12, 2026

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甲状腺功能低下症在肝硬化发病过程中的作用:一项回顾性队列研究和多omics整合分析

Ziyang Yang1,2, Weixuan Liang1,2, Qi Zhang1,2

  • 1Department of Gastroenterology, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

PLoS genetics
|November 7, 2025
PubMed
概括

这项研究确立了甲状腺功能低下症是肝硬化病的因果风险因素,由免疫失调驱动. 研究人员确定了HLA-DQA1和CD27作为肝硬化治疗的潜在治疗点.

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