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Updated: Jan 12, 2026

Competitive Genomic Screens of Barcoded Yeast Libraries
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Competitive Genomic Screens of Barcoded Yeast Libraries

Published on: August 11, 2011

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奥利戈-CALL:一个下一代条码平台,用于研究针对性治疗的耐药性

Yingzhuo Liu1,2,3,4, Yi Ban5,6, Dingcheng Gao1,2,3,4

  • 1Department of Cardiothoracic Surgery, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA.

Science advances
|November 7, 2025
PubMed
概括

新型CRISPR条码系统Oligo-CALL精确追踪细胞系和基因表达,以揭示癌症治疗耐药性的机制. 它确定了DNA修复途径是抵抗的关键,并建议新的组合疗法.

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Amplicon Sequencing using the Long-Read Sequencing Technologies

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Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

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相关概念视频

Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
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