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Updated: Jan 12, 2026

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单细胞剖析揭示了在成功治疗晚期胆囊癌的新辅助疗法后,免疫有利的瘤微环境重塑

Qiu-Yi Tang1,2,3,4, Yi-Jian Zhang1,2,3,4, Zi-You Wu5

  • 1Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

International journal of surgery (London, England)
|November 7, 2025
PubMed
概括

新辅助化疗免疫疗法 (NAT) 通过重塑瘤微环境 (TME) 对晚期胆囊癌 (GBC) 呈现有前途的前景. 这种治疗扩大了有益的免疫细胞,减少了促进瘤的元素,提供了新的治疗策略.

关键词:
癌症干细胞是一种癌症干细胞.化学疗法 化疗 化疗有效的新辅助疗法.胆囊癌是一种胆囊癌.免疫疗法 免疫疗法景观景观 景观 景观 景观三级淋巴体结构的第三级淋巴体结构瘤微环境是一个微环境.

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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