与身体活动相关的死亡率的性别差异在急性冠状动脉综合征之前和之后
Sae Young Jae1, Dong-Hyuk Cho2, Setor K Kunutsor3
1Department of Sport Science, University of Seoul, Seoul, Republic of Korea.
Atherosclerosis
|November 7, 2025
概括
在急性冠状动脉综合征 (ACS) 后增加中度至强度的体力活动 (MVPA) 会降低男性和女性的死亡风险. 这些MVPA变化的生存益处在性别之间是可比的,挑战了以前的假设.
科学领域:
- 心血管医学 心血管医学
- 运动生理学 运动生理学
- 公共卫生 公共卫生
背景情况:
- 之前的研究表明,身体活动 (PA) 的潜在性别差异对心血管结果有好处.
- 假设女性与男性相比,从PA中体验到更大的生存优势.
研究的目的:
- 为了调查与急性冠状动脉综合征 (ACS) 诊断后中度至强度体力活动 (MVPA) 变化相关的性别特异性生存益处.
- 为了比较MVPA变化对ACS后男女死亡风险的影响.
主要方法:
- 来自国家医疗保险服务的30840名被诊断患有ACS的患者的分析.
- 自我报告的MVPA变化分为启动,终止或延续.
- 评估结果包括所有原因和心血管疾病 (CVD) 死亡率,平均随访时间为5.8年.
主要成果:
- 在ACS后启动或继续使用MVPA与男性和女性所有原因死亡率的降低有关.
- 开始和继续使用MVPA还显示,男性和女性的心血管疾病 (CVD) 死亡率降低.
- 统计相互作用分析没有揭示这些死亡率降低关联中的显著性别差异.
结论:
- 在急性冠状动脉综合征诊断后,开始和维持中度至强度的体力活动都与改善的生存率有关.
- 在ACS后的MVPA变化对男性和女性的死亡率好处似乎是相似的.
- 这一发现与女性从体力活动中获得不成比例地更大的死亡率减少与男性相比的观念相反.
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