向早期发现和预防早期发病的结肠直肠癌的方法
Cassandra D L Fritz1,2, Manju George3,4,5, John M Carethers6,7,8
11Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Annual review of medicine
|November 7, 2025
概括
早发性结直肠癌 (CRC) 在50岁以下的人群中正在上升. 本综述强调了导致诊断延迟的患者和提供者障碍,并讨论了早期检测的预防策略.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 胃肠病学 胃肠病学
背景情况:
- 早期结直肠癌 (CRC) 诊断在50岁以下的人群中正在增加.
- 年轻的患者经常经历诊断的显著延迟,尽管出现症状.
研究的目的:
- 审查阻碍早期发现早期发病CRC的临床障碍.
- 概述诊断途径的挑战,并确定改善预防的机会.
主要方法:
- 对早期CRC的诊断途径的文献综述.
- 对及时诊断的患者和提供者层面障碍的分析.
- 检查二次 (查) 和初级 (生活方式) 预防策略.
主要成果:
- 诊断延迟归因于患者和提供者相关的因素.
- 症状识别和早期检测往往是复杂的.
- 有机会加强查和改变生活方式的干预措施.
结论:
- 为了推进早期CRC检测和预防,必须采用多方面的方法.
- 提高公众意识,创新和公共卫生倡议至关重要.
- 解决诊断延迟和改善预防是打击年轻人群中CRC率上升的关键.
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