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Updated: Jan 12, 2026

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坦格雷丁通过改善BMAL1介导的肠壁功能来缓解性结肠炎.

Jiaxian Weng1, Zicong Wu2, Yuwei Huang2

  • 1Institute of Molecular Rhythm and Metabolism, Guangzhou University of Chinese Medicine, Guangzhou, China; Chinese Medicine Guangdong Laboratory, Zhuhai, China.

Biochemical pharmacology
|November 7, 2025
PubMed
概括

坦格雷丁 (TAN) 通过恢复肠道昼夜时钟并增强BMAL1表达,有效治疗性结肠炎 (UC). 这种黄类化合物减少炎症并改善肠道屏障功能,为UC管理提供了新的治疗途径.

关键词:
在BMAL1中,循环节的时钟是循环节的时间.肠道屏障 肠道屏障 肠道屏障在坦格雷丁的坦格雷丁.性结肠炎是一种

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