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Updated: Jan 12, 2026

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
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在BCL-2-瘤微环境轴:免疫抑制的机制,耐药性,以及治疗重编程的途径

Abul Vafa1, Barira Rais1, Nishat Afroz2

  • 1Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi 110062, India.

Critical reviews in oncology/hematology
|November 7, 2025
PubMed
概括

向抗亡性B细胞淋巴瘤2 (BCL-2) 蛋白质可以重新编程瘤微环境 (TME). 这种方法将TME从免疫抑制转变为免疫反应,增强抗瘤免疫力并克服癌症治疗抵抗力.

关键词:
在BCL-2中.在BCL-XL之间.BH3模仿的是 BH3 的模仿.在MCL-1中.灭症 (apoptosis) 是一种死亡的过程.缺氧 缺氧是指缺氧的情况.瘤微环境是一个微环境.维尼托克拉克斯 (Venetoclax) 是一个

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