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Updated: Jul 18, 2026

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
12:07

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

Published on: November 22, 2014

一个模块化的Uba1-纳米体融合使得选择性泛胺转移到标记E2酶

Charlotte Wijne1, Francesca D'Amico2, David A Pérez Berrocal2

  • 1Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.

The Journal of biological chemistry
|November 7, 2025
PubMed
概括

科学家们设计了一种新的泛素激活酶 (Uba1-VHH05),以精确控制泛素的产生. 这种工具将ubiquitin转移指向特定的E2酶,使其能够详细研究它们的功能.

关键词:
在UBA1中,UBA1是UBA1的.乌比奎丁-脱氨探针探测器纳米体是一个纳米体.在任何地方都是无处不在的.无处不在的E2 E2无处不在的化

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