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Updated: Jan 12, 2026

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用于增强温和温度光热疗法的热门双层级纳米酶

Shuyu Wang1,2, Shenghui Wang1, Mengyuan Cao1

  • 1Nanozyme Laboratory in Zhongyuan, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 7, 2025
PubMed
概括

这项研究引入了一种新的纳米酶系统,通过双重抑制热冲击蛋白70 (HSP70) 来克服温和温度光热疗法 (mPTT) 中的耐热性,从而提高了癌症治疗的疗效.

关键词:
级联催化纳米酶是一种催化纳米酶.热冲击蛋白质 70 70 热冲击蛋白质温和温度光热疗法是一种温和温度的光热疗法.热响应行为热响应行为.瘤催化疗法是一种催化疗法.

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Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
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