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Updated: Jan 12, 2026

A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues
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Published on: December 5, 2016

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RNA N6 - 甲基氨酸甲基组协调长非编码RNA,通过激活PI3K信号传递来调解癌症药物耐药性

Yanhong Tan1,2, Changli Zhou1, Sicheng Bian1

  • 1Department of Medicine, The MetroHealth System, Case Western Reserve University, Cleveland, OH, USA.

Cell death & disease
|November 7, 2025
PubMed
概括

长非编码RNAs (lncRNAs) 和RNA N6-甲基氨酸 (m6A) 通过稳定转录来促进白血病药物耐药性. 用PI3K抑制剂向lncRNA-m6A-PI3K通路可以克服耐药性并提高生存率.

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