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Updated: Aug 13, 2026

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
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Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

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基于机器学习的虚拟查和密度功能理论对自然抑制剂的表征,这些抑制剂针对Streptococcus pneumoniae中的突变PBP2x

Avani Panickar1,2, Anand Manoharan3, Sudha Ramaiah4,5

  • 1Medical and Biological Computing Laboratory, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, Tamil Nadu, 632014, India.

Scientific reports
|November 7, 2025
PubMed
概括

这项研究确定了植物化合物Glucozaluzanin C,作为对耐药性肺炎链球菌 (S. pneumoniae) 的潜在抑制剂. 它有效地向突变的青素结合蛋白2x (PBP2x),提供了一种针对抗生素耐药性的新策略.

关键词:
埃莱芬托普斯 (Elephantopus scaber) 是一种食动物.葡萄糖素 c 葡萄糖素 c分子对接是分子对接.分子动态模拟分子动态模拟青素结合蛋白 2x 青素结合蛋白抗B-乳酸盐的耐药性

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Pharmacophore Modeling for Targets with Extensive Ligand Libraries: A Case Study on SARS-CoV-2 Mpro05:50

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