针对乌干达疟疾流行率和风险因素的结构方程建模 (SEM)
Grace Kakaire1,2, Edna Chepkemoi Chumoh3, Mabula Salyungu3,4
1School of Statistics and Planning, Makerere University, Kampala, Uganda. kakairegrace2@gmail.com.
Malaria journal
|November 7, 2025
概括
结构方程建模显示,儿童健康和环境因素对5岁以下儿童疟疾患病率产生重大影响. 针对儿童健康和环境暴露的综合干预措施对于降低撒哈拉以南非洲疟疾负担至关重要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 生物统计学 生物统计学
背景情况:
- 疟疾主要影响撒哈拉以南非洲的五岁以下儿童,并有复杂的促成因素.
- 传统分析很难捕捉影响疟疾传播的多方面的关系.
- 结构方程建模 (SEM) 提供了一种强大的方法来理解这些复杂的路径.
研究的目的:
- 通过使用SEM探索儿童疟疾患病率的潜在和观察到的预测因素.
- 提供对影响儿童疟疾的潜在因素的全面了解.
- 确定影响幼儿疟疾传播的关键途径.
主要方法:
- 利用了2018-2019年乌干达疟疾指标调查 (MIS) 的二次数据.
- 构建了一个带有潜在变量的SEM框架:社会经济地位 (SES),环境,母亲健康和儿童健康.
- 使用标准指数 (CFI,TLI,RMSEA,SRMR) 评估模型的合适性.
主要成果:
- 儿童健康显示,与疟疾状况的积极关联最强 (β=0.22,p<0.001).
- 环境因素表现出边际的负相关性 (β=-0.36,p=0.056).
- 社会经济地位和母亲健康不是统计学上显著的预测因素.
结论:
- SEM有效地解开了影响儿童疟疾的复杂因素.
- 儿童健康状况和环境因素对疟疾患病率至关重要.
- 研究结果支持针对儿童健康和环境暴露的综合干预措施,以减少疟疾负担.
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