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Updated: Jan 12, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
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线粒体生物功能对突然神经感官听力损失的影响:通过孟德尔随机分析探索潜在的机制和关联

Jialei Chen1, Chang Hao1, Xu Tang2

  • 1Department of Otolaryngology Head and Neck Surgery, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Chongqing, China.

Medicine
|November 8, 2025
PubMed
概括

线粒体功能可能会因果关系地影响突然的神经感官听力损失 (SSNHL). 特定的线粒体蛋白质如MUL1,HINT2和GRPEL1显示在SSNHL发育中的潜在作用,提供新的治疗点.

关键词:
在GWAS中,GWAS就是GWAS.门德尔的随机化线粒体的生物功能线粒体的生物功能有关风险因素的风险因素.突然的感觉神经神经听力损失.

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Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
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