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结合健康的生活方式与类风湿性关节炎之间的关联:基于NHANES数据库的横截面研究

Shouyu Miao¹, Xuming Zhang²

¹Department of Rheumatology and Immunology, The First Hospital of Jilin University, Changchun, China.

|November 8, 2025

概括

采用健康的生活方式,包括不吸烟,适度饮酒,身体活动,最佳体重和良好的饮食,与降低患类风湿性关节炎 (RA) 的风险有关. 更健康的行为与较低的RA概率相关.

科学领域:

类风湿病学类风湿病学
预防医学预防医学
流行病学流行病学

背景情况:

类风湿性关节炎 (RA) 是一种具有显著发病率的慢性自身免疫性疾病.
生活方式因素越来越多地被认为是慢性疾病的潜在可修改的风险因素.
了解健康的生活方式与RA发病率之间的关系对于公共卫生战略至关重要.

研究的目的:

调查坚持健康生活方式行为与类风湿性关节炎 (RA) 患病率之间的关联.
量化多个健康生活方式组件对RA风险的影响.
探索这个协会中的潜在的非线性关系和效果修饰器.

主要方法:

利用了来自全国健康和营养检查调查 (1999-2018) 的数据,其中有25,325名参与者.
根据吸烟状况,酒精消耗,体力活动,腰围和饮食,评估健康生活方式得分 (0-5).
采用加权多重回归,子组分析和受限立方线来分析与RA患病率的关联.

主要成果:

在更高的健康生活方式得分和RA患病率之间发现了显著的反向关联.
与0-1行为相比,具有4-5种健康行为的参与者具有明显较低的RA概率 (OR=0.417,P<.001).
年龄被确定为影响修饰因素,健康生活方式得分和RA之间的关系被发现是线性的.

结论:

坚持全面健康的生活方式与类风湿性关节炎的发生有关.
促进多种健康行为可能是预防RA的可行策略.
这些发现强调了改变生活方式在治疗和潜在预防RA方面的重要性.

关键词:

尼汉斯 (NHANES) 是一个名人.健康的生活方式健康的生活方式类风湿症患者的情况吸烟是为了吸烟.腰围腰围腰围腰围

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